Named in honor of John G. Best, a distinguished alumnus and former member of the Board of Trustees, the John G. Best Hall of Science contains classrooms and science laboratories. Best Hall also houses the Fairfield Lecture Room; the Office of the Dean of the School of Arts & Sciences; the Department of Mathematics and Computer Science; the Department of Science; the science laboratories; the Computer Center; Telephone Services; Academic Support services; TSU Middle College director's office and the Department of Criminal Justice, Psychology and Social Sciences.

The University Computer Center houses an academic computer system that consists of Pentium microcomputers running Windows NT Workstation and Windows 2000. The academic system is an Internet site supporting Telnet, WWW and e-mail to other Internet sites. A Microsoft Exchange server handles the e-mail. There are more than 200 computers dedicated to student access in labs across campus. Every room in each dorm is wired to the University network and the Internet.